Total phenolic and total flavonoid content of sugar cane juice and their potency as alpha-amylase inhibitor and anti COVID-19

Diabetes Mellitus (DM) and COVID-19 diseases are still global problems. One of the causes DM, mainly type 2 is unhealthy eating habits, including white sugar, which contains almost no active compounds except sucrose. The in sugarcane juice such as ferulic acid, gallic 4-Hydroxy benzoate vanillic suspected besides alpha-amylase inhibitors, also have potential anti COVID-19. purpose this research to extract secondary metabolites from juice, determine TPC TFC, know silico activity an inhibitor binding position site spike protein. results shown that TFC 0.5501% 0.4480%. analysis has proven acid compound bonded acarbose did. Gallic 4-hydroxy benzoic RBD S protein chloroquine did, with various affinity. These indicate phenolic flavonoids